CREB1 and stroke disorder: In total, 205 genes were differentially expressed between CREB alone vs Control alone (90 up-regulated and 115 down-regulated genes, P value < 0.005) and 1104 genes were differentially expressed between Stroke CREB vs Stroke Control virus (552 up- and 552 down-regulated genes, P value < 0.005) (Fig. 7b).