hM4Di/CREB saline mice demonstrate greater control and faster speed in eating pasta, a reduction in the number of foot faults in grid-walking, improved gait, and preference for the right (affected) paw in exploratory forelimb use in cylinder task starting at 4 weeks after stroke (****P < 0.0001, F (5, 300) = 98.15; Fig. 3d,e, Supplementary Fig. 9). Here, CREB1 is linked to Stroke.