CREB induction in stroke differentially regulates a distributed network of genes with roles in neuronal plasticity or recovery after stroke, including induction of the obligatory NMDA receptor subunit 135 FGF, GDNF, and GH and their receptors36; the transcription factor Sox237; Protocadherin 138 and the calcium-binding proteins, calneuron 139, and calcium-dependent secretion activator 240. This evidence concerns the gene GDNF and stroke disorder.