There were 105 patients (70%) with estrogen receptor-positive (ER+) tumors, 20 (13%) had human epidermal growth factor receptor 2 positive (HER2+) tumors, and 26 (17%) had triple-negative breast cancer (TNBC), determined primarily from metastatic data, and secondarily from primary tumor data. The gene discussed is ESR1; the disease is triple-negative breast carcinoma.