GSTM1 and cancer: Thus we consider features of the Hb signal identifiable from our methods as constituting “conversations” between the vasculature and its host tissue that are conveyed in the “language of hemodynamics.” Also, whether this understanding and other suggested methods actually prove to offer useful benefits or not, we are still left with our explicit demonstration that the identified features have a substantial independence in their sensitivity to a representative disease type (cancer) for a representative tissue class (breast).