TGFB1 and hepatocellular carcinoma: The results suggested that TGF-β1-treated HCC cells had significantly increased colony amounts over the untreated cells, while isoviolanthin (2.5 μM, 5 μM, and 10 μM) treatment dose-dependently inhibited the clonogenic ability of TGF-β1-treated HCC cells (Figure 2C, p < 0.05).