Since PAF is a potent inflammatory mediator that is implicated in several chronic diseases including atherosclerosis and CVD [7], renal disorders [38], cancer [5], HIV infection [39], etc., the novel findings of this study concerning the potent anti-PAF activities of salmon polar lipids seems to provide additional mechanistic evidence for the beneficial outcomes of the dietary intake of salmon and/or salmon oil in such disorders. The gene discussed is PCLAF; the disease is kidney disorder.