A phase 1 trial of patients with newly diagnosed IDH-mutated AML is utilizing standard 7 + 3 chemotherapy (anthracycline for three days and continuous infusion of cytarabine for seven days) in combination with ivosidenib 500 mg daily or enasidenib 100 mg daily for mutant IDH1 or IDH2, respectively [94]. This evidence concerns the gene IDH1 and acute myeloid leukemia.