BRCA1 and ovarian carcinoma: Risk reducing salpingo-oophorectomy (RRSO) is the most effective strategy for preventing ovarian cancer (OC) in BRCA1/2 germline mutation carriers, reducing OC risk up to 96% [1, 2] RRSO is currently recommended to these women after child bearing is complete, at age 35–40 (BRCA1) and 40–45 years (BRCA2).