Although there is some evidence that the inflamed pancreas can produce CXCR3 ligands in individuals with type 1 diabetes [39], it is also possible that these chemokines are produced in response to elevated glucose levels in the periphery, an effect that could be determined by longitudinal measurements of chemokine levels in conjunction with measurements of HbA1c. The gene discussed is CXCR3; the disease is type 1 diabetes mellitus.