In contrast to individuals with rheumatoid arthritis or systemic lupus erythematosus [23], we found that expression levels of CD24 and CXCR3 on switched CD21+CD24+CD27+CD38intCD95+IgD− memory B cells were reduced in individuals with long-standing diabetes. The gene discussed is CXCR3; the disease is systemic lupus erythematosus.