A number of studies has also shown that inhibition of RAS by an angiotensin converting enzyme inhibitor or angiotensin II receptor type 1 (AT1) blocker, can prevent cardiac hypertrophy in hyperthyroidism (Asahi et al., 2001 ▶; Basset et al., 2000 ▶; Basset et al., 2001 ▶; Hu et al., 2003 ▶; Sabri et al., 1998 ▶; Wang et al., 2013 ▶). Here, ACE is linked to cardiac hypertrophy.