It has been shown that C. asiatica treatment significantly reduces oxidative stress such as lipid peroxidation and protein carbonyl and activates antioxidant enzymes e.g. GSH, GSHPx and catalase in both normal adult, normal aging and AD rat model (Hussin et al., 2007 ▶; Jayashree et al., 2003 ▶; Lee et al., 2000 ▶; Veerendra Kumar and Gupta, 2002 ▶, 2003; Zainol et al., 2003 ▶). This evidence concerns the gene CAT and Alzheimer disease.