Compared to the other tumor types, several other canonical and non-canonical WNT signaling pathway factors were not significantly deregulated in PTSMT, in particular, frizzled class receptors (FZD), WNT1-8, WNT9A, WNT10B, WNT11 and WNT16, beta-catenin-related transcription factor 7 (TCF7), WNT signaling pathway regulator adenomatous-polyposis-coli gen (APC), glycogen synthase kinase 3 beta (GSK-3beta), Cyclin D1 (CCND1) as well as the two small GTPase ROH family members ras homolog family member A (ROHA) and cell division cycle 42 (CDC42). This evidence concerns the gene WNT1 and neoplasm.