Specifically, we identified studies that demonstrate health status (HIV-positive serostatus, lower CD4 count) is associated with increased depression [26–30, 38], that mental health disorders may influence HIV risk exposures (sexual risk behaviors [30, 32, 36] and STIs [30, 39]), and that surviving sexual assault may be associated with poor mental health [22–25, 40, 41, 43, 45, 46, 49–51]. The gene discussed is CD4; the disease is depressive disorder.