Recently, variants including P268S, R702W, G908R, and 1007fs in the nucleotide-binding oligomerization domain protein 2 (NOD2) gene, encoding the NF- κB-mediated inflammation related protein NOD-2, were found to be associated with PD in Polish or Chinese patient populations (Bialecka et al., 2007; Ma et al., 2013). The gene discussed is NOD2; the disease is Parkinson disease.