MYO3A and hearing loss disorder: Our results suggest that a combination of 1) complexity of MYO3- multiple cargo system, 2) competition and compensation of the mutant MYO3A with MYO3A WT and MYO3B WT, and 3) proposed redundant function of MYO3B WT in the absence of MYO3A, may contribute to the observed variation in the age of hearing loss onset and extent of progression.