HuR [human antigen R, also known as ELAVL1 (embryonic lethal abnormal vision-like 1)], the ubiquitously expressed member of Hu/ELAV RNA-binding protein family, has been described to regulate the post-transcriptional fate of a number of coding and non-coding RNAs24–26, thereby regulating many cell activities (proliferation, survival, apoptosis, senescence, and differentiation) and affecting broader processes, such as cancer and aging. The gene discussed is ELAVL1; the disease is cancer.