PIK3CD and neoplasm: In particular, we assessed (a) the growth of MDA-MB-231 tumours, which express p110δ in NOD scid gamma (NSG) mice that have defective macrophages and lack T cells (Fig. 2d and Supp Fig. 2) and (b) the growth of the syngeneic 4T1 tumours, which do not express p110δ in the Balb/c strain mice, which have normal macrophages and T cells (Fig. 2e and Supp Fig. 2).