Similarly, the latency of the Rosa26‐Lmo2 + Aid‐Cre T‐ALL was even higher than the latency of Rosa26‐Lmo2 + Sca1‐Cre and Rosa26‐Lmo2 + Mb1‐Cre T‐ALLs (Fig 5C), reinforcing the evidence that the cell‐of‐origin influences the disease malignancy. This evidence concerns the gene LMO2 and acute lymphoblastic leukemia.