NOTCH1 and cancer: Briefly, we found 34 somatic alterations, including eight genes recorded in the cancer gene list, and confirmed recurrent NOTCH1 (SNVs 6/9, indels 1/9), KRAS (SNVs 1/9), NRAS (SNVs 2/9), FBXW7 (SNVs 2/9), and MTOR (SNVs 2/9) mutations (Table 1; Table EV1).