Among the remaining four tumors, three did not contain identifiable pathogenic alterations, and one epilepsy-associated ganglioglioma in the temporal lobe of a young child (SF-GG-37) was found to harbor a novel ABL2-GAB2 gene fusion predicted to result in an in-frame fusion protein containing the entirety of the kinase domain of the encoded Abelson-related protein tyrosine kinase, similar to the ABL2 fusions that have been described in a subset of pediatric leukemias [32, 34]. Here, ABL2 is linked to ganglioglioma.