We expanded this research to different tumor cell types, where we also observed upregulation of some DNA sensors in mammary adenocarcinoma (TS/A) and fibrosarcoma (WEHI 164) accompanied with increased expression of IFN-β and TNF-α.17 We also demonstrated a possible autocrine and/or paracrine pathway through the interferon α/β receptor 1 and tumor necrosis factor receptor 1 (TNFR-1) receptors. Here, TNFRSF1A is linked to neoplasm.