The genes APP, SGSM1, ROR1, PDGFRB, GRIN3A, SEZ6L, NCOR1, FSHR, SLC22A2, TBC1D32, OCA2, and ASAH1, which also encompassed nsSNPs, were classified into Alzheimer’s disease after reference to the GAD. The gene discussed is ROR1; the disease is early-onset autosomal dominant Alzheimer disease.