SEZ6L and early-onset autosomal dominant Alzheimer disease: The genes APP, SGSM1, ROR1, PDGFRB, GRIN3A, SEZ6L, NCOR1, FSHR, SLC22A2, TBC1D32, OCA2, and ASAH1, which also encompassed nsSNPs, were classified into Alzheimer’s disease after reference to the GAD.