In the group of women with PTL, logistic regression revealed that a high CVF VDBP level was independently and significantly associated with the intra-amniotic infection and imminent preterm delivery after adjustment for other confounders (for intra-amniotic infection: gestational age at sampling and maternal CRP; for SPTD within 48 hours: maternal CRP, parity, clinical chorioamnionitis, positive AF culture, and use of antenatal corticosteroids). Here, CRP is linked to chorioamnionitis.