IL1A and autoimmune disease: The human interleukin 1 alpha (IL1A) gene, located on chromosome 2q13 [7], contains some common single nucleotide polymorphisms (SNPs), including rs1800587 (NM_000575.4:c.-949C>T)and rs17561 (NM_000575.4:c.340G>T), which have been reported to be linked to several autoimmune diseases in some populations [8–11].