We also investigated several reported PTK6 substrate candidates that link PTK6 kinase to oncogenic signaling in tumor cells, including Akt [33], Paxillin [34], STAT3/5 [35, 36], ERK1/2 [37], p38 [18], FAK [38] and p130CAS [39]. The gene discussed is BCAR1; the disease is neoplasm.