F3 and ovarian cancer: Previous study also demonstrated that CCC histology was a risk factor for preoperative silent VTE[6] or VTE in the postoperative period.[15,16] Some studies have demonstrated that tissue factor (TF) was expressed at higher rates and at higher concentrations in CCC compared with the other types of ovarian cancer.[17,18] TF, which is a membrane glycoprotein, has an extracellular domain that is not in direct contact with the blood flow.