A total of 73 patients (71.6%) developed GD, 12 patients (11.7%) exhibited hypothyroidism with positive TRAb, HT occurred in 6 patients (5.8%), thyroiditis in 5 patients (4.9%), and hypothyroidism (TRAb negative, anti-TPO antibody negative, or not tested) and hyperthyroidism (TRAb negative or not tested; technetium scan not done) of unknown etiology each occurred in 2 patients; the cause of TD in 2 patients was unknown, and they were lost to follow-up (Table 1). This evidence concerns the gene TPO and thyroiditis.