And, Table 6 presents significant hypo-methylated DMRs and associated genes that showed difference between Cancer versus control groups, with Figure 3 presenting the three most representative genes, SEPT9, SLC2A1/GLUT1andSLC2A3/GLUT3, that were significantly different for both Cancer/control and Family/control pairs, and Supplementary Figure 3 presenting additional genes of significance for Cancer/control pair. This evidence concerns the gene SEPTIN9 and cancer.