CEACAM5 and neoplasm: SAR was significantly associated with age (all groups), gender (stage III RC), CEA level (stage I/II RC), histological type (stage III CRC), tumor depth (CC), nodal status (stage III CC), lymphatic invasion (stage III CRC), adjuvant therapy (stage III RC), recurrence within 1 year (stage III RC), M1b recurrence (stage II/III CRC), liver metastasis (stage II RC), peritoneal metastasis (CC and stage III RC), local recurrence (stage II CC), and treatment after recurrence (all groups) (Table 5).