Specifically, PAK5 E144K has been observed in colorectal adenocarcinomas, PAK5 S364L in lung adenocarcinomas, colon adenocarcinomas, and uterine endometrioid tumors, and PAK5 D421N in multiple lung adenocarcinomas [51, 70-73]. The gene discussed is PAK5; the disease is lung adenocarcinoma.