RAG1 and infection: It is important to remark that though Rag1-/- mice have no mature T and B lymphocytes (Mombaerts et al., 1992), develop totally normal granulocytes, like WT mice, as has been demonstrated in reports which use these mice in infection models (Smith et al., 2009; Seymour et al., 2015; Carey et al., 2016; Papp et al., 2016).