A significant association between SLC30A8 gene 807C/T polymorphism and T2DM was found in the Chinese population under allelic (OR: 0.85, 95% CI: 0.80–0.91, P = 7.42 × 10−7), recessive (OR: 0.52, 95% CI: 0.38–0.72, P = 8.49 × 10−5), dominant (OR: 2.40, 95% CI: 1.68–3.41, P = 1.30 × 10−6), homozygous (OR: 0.52, 95% CI: 0.40–0.67, P = 2.90 × 10−7), heterozygous (OR: 0.79, 95% CI: 0.71–0.88, P = 1.63 × 10−5), and additive genetic models (OR: 0.73, 95% CI: 0.64–0.83, P = 7.05 × 10−7) (Figures 1–6; Table 2). The gene discussed is SLC30A8; the disease is type 2 diabetes mellitus.