In obese women with endometrial and breast cancer, the level of apelin-36 is also increased and positively correlated with BMI, fasting insulin levels, metabolic changes in fat tissues, hyper-inflammation, and neovascularization (Altinkaya et al., 2015; Cabia et al., 2016; Salman et al., 2016). Here, APLN is linked to breast carcinoma.