Translocator protein (18 kDa, TSPO), which was initially designated as the peripheral-type benzodiazepine receptor (PBR), was identified in 1977 when investigators were searching for peripheral tissue binding sites for benzodiazepines, one of the most widely available class of drugs prescribed to treat patients with anxiety, convulsions, or insomnia [1]. The gene discussed is TSPO; the disease is insomnia.