In addition to described roles in hematologic malignancies, prostate cancer, breast cancer, and pancreatic cancer, the noncanonical NF-κB pathway and its components have been shown to support the proliferation, survival, or tumor initiating cells of glioma [68,69], ovarian [70], and endometrial cancers [71]. Here, NFKB1 is linked to familial pancreatic carcinoma.