CD274 and non-small cell lung carcinoma: Overall, these results support using PD-L1 immunostaining cut-off points to select patients with higher chances of responding to PD-1/PD-L1 checkpoint inhibition, as they are consistent with previous positive correlations of PD-L1 expression, numbers of TIL, and longer overall survival in NSCLC and other solid tumors [15, 20–21, 22–23].