NFKB1 and neoplasm: 9B). Furthermore, quantitative immunohistochemistry with antibodies to pRelA536 indicated ex vivo exposure to low dose aspirin induced NF-κB pathway activation in 3/6 tumours (Figure 7C). Importantly, for individual tumours, there was a very strong inverse correlation (r2 = –0.85, n = 6) between aspirin effects on TIF-IA and RelA536 phosphorylation (Figure 9D).