When comparing HER2-IHC 3+ breast tumors with the HER2-IHC 3+ BT474 cell line,38 we observed that HER2 expression had higher variance in clinical Tumor 0909 and Tumor 0903 biopsies by scWB (F-test, Ft0909-BT474 = 8.41 > F89,390(0.05) = 1.44, p < 0.01; Ft0903-BT474 = 1.8 > F126,390(0.05) = 1.38, p < 0.01). The gene discussed is ERBB2; the disease is breast neoplasm.