PTEN and diffuse intrinsic pontine glioma: Our data strengthens the association with <i>PTEN</i> loss in diffuse intrinsic pontine gliomas and provides further argument for the inclusion of <i>PTEN</i> in future targeted sequencing panels for pediatric diffuse intrinsic pontine gliomas and for the development and optimization of mTOR/PI3K inhibitors with optimal central nervous system penetration.