The expression of LMP2A could be detected in more than 50% of NPC cases.71 LMP2 promotes cell survival, stemness, EMT, which may related to the metastatic phenotype.72–74 Also, LMP1 and LMP2A function cooperatively to promote carcinoma development specialy in NPC.11, 75. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.