PDLIM7 and cancer: They found that LMP1 increases the localization of phosphatidylinositol 3-kinase (PI3K) and Akt to lipid rafts which reorganizes membrane and cytoskeleton microdomains to modulate signal transduction.12 Also, LMP1 increases the expression of some cancer progenitor cells (CPC) markers and induced a CPC-like phenotype in epithelial cells.13