DOK6 and gastric cancer: In a typical gastric cancer harboring this abnormal chromosome, truncation of DOK6 intron 4 was evident with break-apart BAC probes flanking the breakpoint (RP11-22G18; chr18:67,564,184–67,743,728 labeled with SpectrumGreen and RP11-98M3; chr18: 67,198,763–67,355,215 labeled with SpectrumOrange) (Fig. 1i).