Autoantibodies target Dsg3 (130 kDa) in patients with mucosal pemphigus vulgaris (PV), Dsg1 (165 kDa) in patients with pemphigus foliaceus (PF), and both in patients with a mucocutaneous form of PV (Amagai et al., 1999, Amagai et al., 1999, Kershenovich et al., 2014). The gene discussed is DSG3; the disease is pemphigus foliaceus.