CTSL and stroke disorder: In contrast to reductions in genes associated with macrophage activation, expression of genes associated with phagocytosis through lysosomes, Lamp2 (Figure 4A), and proteolytic processing of phagocytosed material, Ctsl (Figure 4I) were upregulated after experimental stroke suggesting that mechanisms necessary for subsequent phagocytic clearance of pathogens may be unaffected by stroke.