TRIM22 and tropical spastic paraparesis: As shown in Figure 3B, significant positive correlations were confirmed between TRIM5α/TRIM22 (p = 0.005, r = 0.50) and TRIM5α/BST2 (p < 0.001, r = 0.67) in both HTLV-1-infected AC (n = 17) and HAM/TSP patients (n = 10).