Studies have confirmed that disorders of hepcidin are a main contributing factor to chronic anemia in patients with infections and tumors (Reichert et al., 2017) and that hepcidin is involved in the pathological processes of hereditary hemochromatosis, thalassemia and iron deficiency anemia (Girelli et al., 2016; Daher et al., 2017). This evidence concerns the gene HAMP and thalassemia.