IGF1 and cancer: While in healthy subjects, MBIs had no effect on cytokine levels, except for an increase of insulin-like growth factor 1 (IGF-1) (Sanada et al., 2017), the effects were more pronounced in cancer patients, albeit with contradictory results including changes in the concentration of IFN-γ and IL-4, a decrease in TNF-α and IL-10, and no differences in the level of IL-6 (Sanada et al., 2017).