LEF1 and neoplasm: The expression of AXIN2 and LEF1 was significantly higher in tumours harbouring a ∆(2 + 3) deletion in comparison to those without mutations in analyzed genes (ACC wildtype (n = 39) vs ∆(2 + 3) deletion (n = 4), p = 0.0039 and p = 0.0090 respectively) and was comparable to the tumours harbouring CTNNB1 missense mutations (ACC wildtype (n = 39) vs CTNNB1 mutants (n = 5), p = 0.0211 and p = 0.0451 respectively; Fig. 3b).