VENTX and malignant colon neoplasm: To further determine whether the inhibition of tumorigenesis in the NSG-PDX mice is related to VentX-regulated TAM polarity 1 week post implantation of fragments of colon cancers, the NSG-PDX mice were tail-vein injected with in vitro M1-differentiated TAMs transfected with either VentX-MO or control-MO.