VEGFA and neoplasm: The M2-like TAMs show an elevated expression of interleukin (IL)-10, matrix metallopeptidase (MMP), and vascular endothelial growth factor (VEGF), but decreased expression of pro-inflammatory tumoricidal cytokines, cytotoxic inducible nitric oxides (iNOs) and reactive oxygen intermediates (ROIs), and are thought to be supportive of tumor growth6.