As both miR‐200c and miR‐375 act both on the mRNA level and on translation of QKI‐5, this ZEB1/miR‐200/miR‐375/QKI‐5 regulatory loop is particularly strong, producing the strongly mesenchymal expression pattern of QKI we observed in the panel of breast cancer cell lines that we examined, paralleling the mutually exclusive expression of miR‐200c and ZEB1 (Gregory et al, 2008). The gene discussed is QKI; the disease is breast carcinoma.