CD4 and neoplasm: Logistic regression multivariate models incorporating tumor stage corroborated the association between survival and higher epithelial and stromal densities of TAMs (CD68+) (P = 0.044; hazard ratio [HR], 0.506; 95% confidence interval [CI], 0.261–0.982) and higher epithelial density of helper T cells (CD3 + CD4+) (P = 0.097; HR, 0.547; 95% CI, 0.269–1.114) (Additional file 8: Table S3).