Of these, S100A8, S100A9, S100A12, IL-8, MMP8 and MMP9 encode antimicrobial peptides (AMPs) or chemoattractant molecules previously known to be involved in GPP pathogenesis, and PLK1 and IRF7 were identified in the current research. Here, CXCL8 is linked to psoriasis 14, pustular.