Currently, IHC markers for medulloblastoma subtyping, such as WNT, GAB1 or YAP1, are not universally performed and subtyping by IHC does not always coincide with subtyping by other methods (Nanostring, 450k array profiling),[14] indicating that these IHC markers cannot yet be used to select therapeutics for patients. This evidence concerns the gene GAB1 and medulloblastoma.